What does dependence mean in the context of drug use?

Dependence, in the context of drug use, refers to a state in which an individual requires a drug to maintain normal physiological or psychological functioning. This condition arises when the body adapts to a substance, leading to tolerance and withdrawal symptoms if the substance is reduced or discontinued. As a result, individuals may feel compelled to continue using the drug to avoid these negative effects and to function normally.

This definition highlights the significance of physical and psychological reliance on a drug, which can develop with regular use. It underscores the importance of understanding both the medical and emotional implications of dependence, particularly in treatment contexts where managing withdrawal and determining the need for continued medication are critical.